With more than 15 years of industry experience, BIO-TIDE is an R&D-driven OEM/ODM/OBM enterprise focusing on biomedicine and beauty skincare. We have built a dual-driven R&D system combining fundamental research and applied research, taking technological innovation as our core competitiveness.
We integrate the group’s full industrial chain resources covering raw materials, manufacturing, customization, branding and marketing. Our dual-research and dual-production base creates a complete closed industrial loop ranging from raw material development to end-market terminals.
2011-2013 Established Dongshengyuan Research Institute focusing on cosmetic R&D 2014 Shanghai Yuanben Skincare Co., Ltd., focusing on maternity & infant skincare, founded 2015-2017 Dedicated to developing products suited to Chinese skin and building a benchmark in light medical beauty skincare
2018 oint Laboratory with Korea Institute of Skin Science — Dongshengyuan Research Institute officially launched Strategic Partner of China Beauty Expo 2019 Partnered with global top suppliers for imported raw materials from the US, Germany, France and beyond.
2020 Awarded Excellent Innovative R&D Team at China Cosmetic Technology Festival 2021 Strategic cooperation with Japan Hanajirushi; launched Asian Skin Science Program and built Asian Skin Property Database BIO-TIDE Skin Science Research Institute founded with 34 exclusive patents
2022 In-house testing laboratory obtained CMA accreditation Certified by MIIT for Integration of Informatization & Industrialization, qualified for Grade-A cosmetic CRO managemen Cooperated with expert teams to develop exclusive fermented functional raw materials
2023 Guangdong Youxue Pharmaceutical Technology Co., Ltd. founded as our industrial manufacturing base Cooperated with Guangdong Provincial Institute of Chinese Medicine, owning multiple patents on plant sunscreen and preservatives Strategic cooperation with Guangdong Weilandi Medical Technology
2024 Cooperated with Fujian Special Food Association to draft national group standard for tremella polysaccharide Launched supply chain formula R&D project with Guangdong Radio & TV Transportation Group Appointed designated supplier of special products for China Railway Guangzhou Group
2025 Strategic cooperation with Beijing Tongrentang, ranked TOP1 within its supply chain Co-established Gene Skincare Research Institute together with Zhongzhi Biotech Guangdong Youxue Pharmaceutical Technology certified as High-tech Enterprise
Professor of Formula R&D
Founder, Chairman & Chief Formulator of BIO-TIDE, known as "Peptide Dad". He is a senior expert in China’s cosmetic industry. He owns 25 patents and one SCI paper, and is a pioneer of small-molecule peptide research. As one of China’s first generation of cosmetic formulators from CAS。
he boasts decades of technical experience. He works as a distinguished expert, visiting professor at multiple universities and Professor at Korea Institute of Skin Science. leading core research projects and taking technical roles in many cosmetic institutions.
Founder & Chief Formulator of BIO-TIDE. Trained under renowned industry experts Professor Xu Liang and dermatologist Liu Wei. With over 20 years of experience, he has served more than 600 brands and accumulated tens of thousands of mature skincare formulas.
研发优势 — 国际专家团队
Quickly responding to regulatory trends, we build world-class global R&D solutions supported by senior expert advisors.
scientific advisor of Dr. Aier Skin Microecology
Professor, International Cosmetic College, Shanghai Institute of Technology A pioneer in skin microecology & skin epigenetics research, focusing on microecological skincare development.
Professor of the School of Chemistry and Materials Engineering, Beijing Technology and Business University.
Director of the Key Laboratory of Light Industry Cosmetics of China. she has published more than 50 professional papers and serves as director of China Association of Chinese Medicine and chief physician at China Academy of Chinese Medical Sciences.
Director of the Cosmetics Department, Beijing Technology and Business University.
Vice Chairman of the Cosmetics Regulation Committee of China Drug Administration Research Society. He has published 3 monographs and over 50 papers, and presided over the formulation of 6 industry standards.
Korea Institute of Skin Science.
PhD in Bioengineering and Professor of Fragrance & Cosmetic Science at Konkuk University. PhD in Bioengineering and Professor of Fragrance & Cosmetic Science at Konkuk University. Board member of the Asian Journal of Beauty and Cosmetics
Professor at the International Cosmetic College, Shanghai Institute of Technology.
Proponent of the precision skincare concept and founder of skincare brands. Initiator of the Cosmetics Committee of Chinese Pharmaceutical Association. Proponent of the precision skincare concept and founder of skincare brands.
PhD in Biochemistry and Molecular Biology, Chinese Academy of Sciences.
Long engaged in research on camellia and soapberry plant extracts. Leader of botanical active ingredient projects.
We conduct formula discussion, skin mechanism research and raw material compatibility testing in our R&D lab. Supported by a mature formula library and 36 exclusive patents,BIO-TIDE Skin Science Research Institute cooperates with authoritative institutions and selects premium imported raw materials.
We deliver one-stop R&D solutions for emerging brands, professional skincare and Class II medical cosmetics, developing differentiated, safe and science-backed products.
Strong scientific research strength relies on high-standard facilities. BIO-TIDE builds integrated R&D spaces including meeting rooms, testing labs and sample preparation zones. Tailored for cosmetic formulation research, these spaces support our team to carry out rigorous and efficient R&D work.
We establish regular cross-department communication to align market demands and R&D progress. The marketing team shares consumer trends and client needs, while the R&D team advances formula upgrading and new product planning.
生产优势
Before launch, new packaging materials undergo comprehensive tests including compatibility, sealing performance and stability. Incoming materials are inspected on texture, cleanliness and compression resistance to ensure safety and compliance.
Each batch of raw materials is tested for appearance, pH value, viscosity, active content, microorganisms and other indicators to guarantee safety, efficacy and reliability.
Every batch of semi-finished and finished products is tested for appearance, skin feel, stability and microorganisms to strictly control product quality..
Adopting multi-stage ultra-pure water system with water quality superior to industry standards. Circulating water is disinfected by UV lamps and monitored daily to guarantee stable water quality.
We own a 100,000-class dust-free GMP workshop. Regular microbial monitoring on airborne bacteria, equipment and staff maintains high sanitation standards.。
First article confirmation is required before mass production, with full-process inspection for each working procedure. Complete production records and sample library enable full-chain traceability for continuous quality improvement.
Strong R&D strength is supported by standardized production. Youxue runs a modern compliant factory featuring integrated R&D, testing and manufacturing. We follow cosmetic cleanroom standards and rigorous quality control to turn custom formulas into safe, consistent finished products for partners.
BIO-BITE commits to “empowering emerging brands with growth genes and empowering established brands with technological core strengths.”
Strong R&D strength relies on standardized production. Youxue runs a modern compliant factory, while BIO-TIDE delivers integrated R&D, testing and manufacturing. Adhering to cosmetic clean standards and rigorous quality control, we turn custom formulas into safe。
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+1 (415) 555-0142
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201 Mission Street San Francisco, CA 94105
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